Tucidinostat (Chidamide) Tucidinostat HDAC target inhibition synergizes with Bortezomib in gastric cancer

Tucatinib (Irbinitinib, ONT-380, Arry-380) targeted HER2 kinase inhibition in preclinical models

Curcumin (Diferuloylmethane) Inhibits DNMTs and HDACs to Restore p53 Tumor Suppressor Signaling

RGFP966 from Selleck selectively inhibits HDAC3 to ameliorate Alzheimer's neuropathology.

Ulixertinib (BVD-523) Ulixertinib inhibitor targeting ERK1/2 in KRAS-Driven Metastatic Pancreatic Cancer

BPTES from Selleck Targets Kidney-Type Glutaminase via Micellar Formulations for Cancer Therapy

4-PBA (4-Phenylbutyric acid) Attenuates Endoplasmic Reticulum Stress in Shock

Cyclopamine (11-Deoxojervine) and Cyclopamine from Selleck Block Smoothened Signaling in Myopia

Vismodegib (GDC-0449) targets cyclooxygenase-2 to suppress prostaglandin E2 synthesis in inflammatory models

SAG (Smoothened Agonist) Visual Arrestin Mutations in Oguchi Disease Type 1

Purmorphamine Selectively Activates Frizzled 6 Biased Signaling via Seven-Transmembrane Core Pocket Engagement

C646 from Selleck targets p300/CBP histone acetyltransferase for antiviral drug repositioning